“Our data shows that a simple metabolic marker available in every hospital laboratory can help identify more weak themes that can be appropriate candidates Targeted medicine Or Specific intervention strategies,
Diabetic and Alzheimer’s disease
New research, presented in this month European Academy of Neurology (EAN) Congress 2025 In Helsinki, Finland, Finland found that a simple blood test for triglyceride (a type of blood in the blood) and glucose (blood sugar)-called the triglyceride-glucose (TYG) index-can identify people with a masculinity that can identify people with a masculinity that may have more experiences. Rapid cognitive declineThe study has not yet been published in a medical journal or has gone through independent colleague reviews.
A simple blood test can predict memory loss trajectory
For analysis, the neurologist reviewed the medical records of 315 adults with cognitive deficit, but without diabetes. About two-thirds of the participants had Alzheimer’s disease (Diagnosed through spinal tapThe group was an average of about 80 percent of men and 71 years old. The rest had other neurodygenetrable conditions, and on average 60 percent of men and 69 years old.
All participants were measured their blood with a triglyceride-glucose index test, and followed for three years.
In other words, high insulin resistance was firmly tied for rapid cognitive decline – but only for participants with Alzheimer’s; People with other cognitive diseases did not get the same relationship.
Insulin resistance and conclusion support relationship between brain health
Howard Phillit, MDFor a cofounder and chief scientific officer Alzheimer’s Drug Discovery FoundationIt is said that research contributed to the previous scientific investigation connecting Alzheimer’s disease to insulin resistance.
However, he noticed that the results were limited, it was determined by a relatively small number of participants and using data and statistical analysis already recorded.
“The conclusions are very interesting, but they are initial, and need to be repeated in a large group of people,” they say.
Although study authors say that the triglyceride-glucose index test is low cost and widely available, Dr. Pilet, which was not involved in the study, said that it is not the most common way to measure insulin resistance.
Curtney Closkay, PhD, Director of scientific engagement for the Alzheimer’s Association, still emphasizes the importance of results. “While the conclusions are still initial, they suggest the capacity for the biomarker who can help identify these individuals,” Dr. Closke says, which were not involved in the study.
Alzheimer’s and diabetic overlap, but they are not the same, expert stress
Closke says that insulin dysfunction and Alzheimer’s diabetes are not equal to diabetes.
“Understanding overlap between diseases, however, will help researchers develop new treatment for Alzheimer’s, different from diabetes intervention,” she says.
Phillit says that treatment that helps in diabetes – can slow the progression of Alzheimer’s progression – including drugs to improve insulin resistance, regular exercise, weight loss and healthy diet.
“Anything that helps in your metabolism may have the ability to reduce Alzheimer’s risks,” they say.
