A new study has identified the elemental-pregnancy intestinal microbyota signature associated with the development of gestational diabetic mellets, a metabolic disorder that takes sufficient risk to the health of both maternal and fetus. The Study, Published in American Society for Microbiology Journal Microbiology spectrumThe pregnancy provides new avenues for prevention and management of diabetes.
Gestational diabetes is a prevalent metabolic disorder characterized by abnormal glucose metabolism, mainly in the middle of late stages of pregnancy. Preliminary intervention for pregnancy diabetes can significantly reduce complications for both mother and baby. Gestational diabetes enhances the risk of maternal complications such as gestational hypertension, polyhydramas, and cesarean delivery, while also causing long -term health risks for the fetus, including asphicks at birth and adults have increased sensitivity to obesity and diabetes.
In the new study, the second hospital, researcher of the Southern Medical University, and the third affiliated hospital of Guangzhou Medical University, all Guangzhou, have been determined to identify in China, Intestine microbiota Dysbiosis that is strongly associated with the onset and progress of gestational diabetes that can serve as an important initial-warning biomarker. Scientists analyzed fecal microbyota of 61 pregnant women during their first trimester of pregnancy using 16S RRNA sequencing. He then corrected these microbial profiles with oral glucose tolerance test results in 24–28 weeks of pregnancy and clinical distribution results.
Researchers found that there were significant differences in intestinal microbyota structure among women with pregnancy diabetes and healthy pregnancies. Based on their findings, researchers developed an early clinical model for genius-level markers, with high clinical precision, genus-level markers.
“These findings suggest that microbiota-based equipment may be able to find out quick, non-invasive detection gestational diabetes mellitusOffering new opportunities for prevention and personal management, “Write the study authors.” This research highlights the role of the intestine Microbiom There are important implications in pregnancy and to improve maternal and fetal health results. ,
