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Saturday, 28 June 2025
Medical News

Pregnancy complications linked to higher long-term stroke risk in women

Pregnancy complications linked to higher long-term stroke risk in women

Women who experience complications during pregnancy face more risk of stroke in the next decades European Heart Journal Today (Tuesday).

The study, which included data on more than two million women over 40 years, found an increased risk for women who had diabetes or high blood pressure when pregnant, a preterm delivery or high blood pressure for a child weighing.

Researchers say that these common pregnancy complications can serve as an initial signal for future heart problems, which means that women can help in life quickly to reduce the risk of their stroke.

A stroke occurs when blood supply to the brain part is cut off, hungry brain cells of oxygen and leads to possible cognitive and pioneer for physical disability.

The study was led by Professor KC Nerp from the Department of Family and Community Medicine at Uthealth Houston, USA. He said: “We know that pregnancy is a ‘natural stress test’ that heart disease can actually reveal the risks of high heart disease before developing.

“One of all pregnancies is affected by one of these complications up to a third of all, however, long -term cardiovascular risk for these women are poorly understood and hence is often not considered in their regular clinical care.”

Researchers used data from a Swedish National Corort of all 2,201,393 single conception between 1973 and 2015. About 30% of women (667,774) experienced at least one of the following complications: Preater delivery (less than 37 weeks), hypertension during pregnancy (diabetes (high blood sugar).

Researchers also collected data on which women experienced a stroke in the next years by 2018 and compared the stroke rates among women who did not have complications and women of pregnancy.

The risk of stroke for women with high blood pressure (not pre -philanumsia) or high blood sugar during pregnancy was almost doubled. For women who had a preterm delivery, the risk of stroke was approximately 40% higher, for women with pre -plampsia, the risk was about 36% more, and for women whose children were born younger for their gestational age, the risk was about 26% more. There were even more risk in women who experienced two or more of these complications.

Increased risks in the first 10 years after delivery were generally the highest, but 30 to 46 years after pregnancy continued in women’s lives. However, for women who had pregnancy diabetes, the increased risk over time also increased.

Researchers compared the risk of stroke between sisters in the corket, which share the same genetic and environmental risk factors for strokes, but they found that it was not completely responsible for the link between complications and strokes during pregnancy.

For our knowledge, this study is the greatest to examine many pregnancy complications in relation to long -term stroke risk in women. In addition, it is the first to assess whether families can share factors that prevent both for pregnancy adverse results and strokes, but shared family factors did not appear to explain our conclusions.


These pregnancy complications share some common characteristics, including placental abnormalities and SwellingThis can potentially affect the structure or function of small blood vessels. Those changes in small blood vessels sometimes proceed after pregnancy, and it can be a factor in women’s high risk.


Both women and their doctors should now identify that pregnancy complications are an initial signal to the risk of future stroke. This can help us identify high risk women before suffering from a stroke or other heart disease. Women who experience these complications require support to reduce other heart risk factors, including obesity, physical inactivity, unhealthy diet, smoking, hypertension, diabetes and high cholesterol. These interventions should be implemented as soon as possible, followed by long -term monitoring to reduce their stroke risk in the life course. ,


Professor KC Nerp, Family and Community Medical Department, Uthelth Houston

Editorial Dr. from Michigan University, USA. In Abbi Lane, said: “Stroke is a major cause of death and disability that can occur before different risk factors in women. European Heart Journal Addressing this important requirement by strictly define the associations between the adverse pregnancy results (APOs) and strokes by the adverse and colleagues. Appos were not rare; 30% of women experienced at least one APO. All APOs were significantly associated with 46 years of follow -up strokes […],

“Perhaps more attention should be paid to psychological and emotional tolls associated with APOs. […] Not only the complex pregnancy/birth causes itself stress, but the psychological and/or medical sequence of the APO can last for months or years. […] Managing medical and neurodevaluate disorders can lead to emotional, logical and financial stress of months or years for parents.

“The effects of psychological stress can eventually appear to stroke through two potential over -wide routes: direct physical effects and poor copying behavior.

Reactions to stress that are also initial events in the development of overt stroke risk factors. […] High stress is associated with lifestyle and adverse effects on copy behavior, including

Smoking, worse medicine, poor diet, low physical activity and high weight of the body.

“Disrupting the cascade from APO to stroke may include a versatile approach to control blood pressure and can soon be addressed to variable lifestyle habits affecting physical and mental health after APOS.

“As APOS parous 30% occurs in parous people and stroke, 90% to be stopped, applying a multilateral, preventive intervention, which soon seems like a clear victory after delivery.”

Source:

Journal reference:

Additional, C., et al. (2025) Adverse pregnancy results and long-term risk of stroke: study of a Swedish nationwide co-brother-sister. European Heart Journal, doi.org/10.1093/eureartj/ehaf366,

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