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Bone growth occurs through the proliferation of special cells of cartilage tissue, which is known as chondocytes at both ends of a bone. This process requires synthesis of external matrix (ECM) in bone growth plates. A peptide hormone, known as a C-type natyuratic peptide (CNP), plays an important role by binding to its specific receptors […]
Huntington’s disease has long tried to save the afflicted neurons. A new study in Cell report Shows that the adult animal model of the disease has not only slowed the motor and cognitive decline, but also extended the life span. These findings change our understanding of Huntington’s pathology and open a possible passage for cell-based […]
A new study suggests that estrogen fine-tunes gut cell communication to increase serotonin-powered pain. Study: A cellular base for increased intestinal sensitivity in womenImage Credit: Prathankarnpap / Shutterstock *Important Information: Biorxiv Publishes preliminary scientific reports that are not reviewed by colleagues and therefore, it should be considered as decisive, guide clinical practice/health related behavior, or […]
Researchers at the Karolinska Institute and Lund University in Sweden have identified a new treatment strategy for neuroblastoma, an aggressive form of childhood cancer. By combining two antioxidant enzyme inhibitors, they have converted cancer cells into healthy nerve cells in mice. Study is published in the magazine Action of National Academy of Sciences (PNAS). Neuroblastoma […]
Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. About 80% of people with MS are inflamed in the cerebellum, the part of the brain that helps control movement and balance, possibly leading to troubles with shocks, poor coordination and motor control. These problems often persist and can deteriorate over time, as the cerebellum […]
Scientists at the University of UCLA and the University of Toronto have developed an advanced computational equipment, called moppagen, which helps identify invisible genetic mutations in protein, unlocking cancer research and further new possibilities. The equipment is described in Nature biotechnologyIt will help to understand how changes in our DNA affect proteins and eventually contribute […]
CD19- Car T-cell treatment is a novel option of deep B cell deficiency with promising results in various rheumatologic and musculoskeletal diseases (RMD). This and other cell -depleting approaches can effectively reset the immune system – with the capacity of durable reaction without chronic immunosuration. The European alliance of unions for eular – rheumatology – […]
Pembrolisabeb, an immune checkpoint inhibitor, has been approved by the US Food and Drug Administration (FDA) for the treatment of patients with advanced head and neck squamous cell carcinoma, whose tumors express PD-L1, whose tumors express PD-L1 [Combined Positive Score (CPS) ≥1] As determined by a test approved by the FDA. FDA Approval Pivotle Keenote-689 […]
Researchers at the Vib-Ku Leuven Center for cancer biology have revealed how a unique interaction between two cellular coaches, ie endoplasmic reticulum (ER) and mitochondria, can act as a central ignition point for ferroptosis, which is a form of a formation of the cell death by lipid oxidation and iron. In a study published in […]
Women with breast cancer, who were also carriers of BRCA1 or BRCA2 mutations and after mastectomy, were received as part of their reconstruction surgery, the texture was received as part of the surgery, the possibility of developing a rare T-sail lymphoma, a rare T-sail lymphoma, was likely to develop a rare T-sail lymphoma. According to […]
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