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research background Cuproptosis represents a novel system of cell death, characterized by intracellular copper ion accumulation. Unlike other cell death passages, its unique process has created significant interest in the treatment of inflammatory bowel disease (IBD) and colorectal cancer (CRC) due to its promising applications. Emerging evidence suggests that copper metabolism and cupoptosis can play […]
Human eggs are some of the most patient cells in the body, until the necessary decades are inactive. A study published today The Ambo Journal Shows that cells deliberately slow down the activity of their internal waste disposal systems as they mature, most likely a evolutionary design that reduces metabolism and damage in the bay. […]
In recent years, the regulatory role of the intestine microbyota in the initiation and progress of colorectal cancer (CRC) has attracted increasing attention. In major microbial contributors, Dhut (FN) has been identified as an important pathological factor in CRC. As an oral anaerobic chemical, FN is rarely found in the low gastrointestinal tract of healthy […]
Adenosine Deminus 2 (ADA2) plays an important role in immune regulation, especially in monocyte discrimination and activation. Unlike Ada1, which mainly serve intracellularly, the ADA2 can be secreted or smuggled to lysosomes. Decreased ADA2 (DADA2) due to impaired discrimination in TNF-α levels, highly supporters inflammatory cytokine production, and monocytes, impaired discrimination in anti-inflammatory M2 macrophages. […]
Bone growth occurs through the proliferation of special cells of cartilage tissue, which is known as chondocytes at both ends of a bone. This process requires synthesis of external matrix (ECM) in bone growth plates. A peptide hormone, known as a C-type natyuratic peptide (CNP), plays an important role by binding to its specific receptors […]
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