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Sunday, 27 July 2025
APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s
Medical News

APOE ε4 variant reveals hidden risk factors beyond Alzheimer’s

A groundbreaking study suggests how a single gene variant shapes the immune landscape of the brain and blood, unlocking new opportunities for early detection and intervention in Alzheimer’s, Parkinson’s, and other neurodogenic disorders. Study: Apoe of4 carriers share immune-related protective changes in neurodigenerative diseasesImage Credit: Andrii Vodolazhskyi / Shutterstock In a recent study published in […]

New UAB-developed gene therapy for ALS receives orphan drug designation
Medical News

New UAB-developed gene therapy for ALS receives orphan drug designation

The US Food and Drug Administration (FDA) has given an orphan drug design for a new gene therapy for the Ameotrophic Lateral Sclerosis (ALS) developed in Universitate Autonem de Barcelona and US company Clotho Neurosis, Inc. The drug uses a viral vector of AAV (Adeno-Juda Virus) type that expresses neuroregensing, antioxidants and anti-inflammatory properties with […]

Immune cell signatures explain variations in systemic sclerosis severity
Medical News

Immune cell signatures explain variations in systemic sclerosis severity

Treatment of rare diseases can be the best time complex, and it becomes even more complicated when various patients with the same disease display different symptoms. Now, Japanese researchers have reported a cellular signature that can explain why some patients with autoimmune disease are stable while others face complications of life-threatening. In a study to […]

Mitochondrial dysfunction drives cerebellar damage in multiple sclerosis
Medical News

Mitochondrial dysfunction drives cerebellar damage in multiple sclerosis

Multiple sclerosis (MS) affects an estimated 2.3 million people worldwide. About 80% of people with MS are inflamed in the cerebellum, the part of the brain that helps control movement and balance, possibly leading to troubles with shocks, poor coordination and motor control. These problems often persist and can deteriorate over time, as the cerebellum […]

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases
Medical News

Deep B cell depletion offers new hope for rheumatologic and musculoskeletal diseases

CD19- Car T-cell treatment is a novel option of deep B cell deficiency with promising results in various rheumatologic and musculoskeletal diseases (RMD). This and other cell -depleting approaches can effectively reset the immune system – with the capacity of durable reaction without chronic immunosuration. The European alliance of unions for eular – rheumatology – […]

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