Mitochondrial protein misfolding found to kill pancreatic cells in type 2 diabetes
A aging-related diseases including cancer, heart disorder and type 2 diabetes are associated with defects in protein synthesis and folding. Previous studies have shown that protein misfolding occurs in insulin-produced β-cells Patients with type 2 diabetesThese cells are found in pancreatic islets. The stress is believed to be mainly within the endoplasmic reticulum, which is […]