People with an underactive thyroid may increase the risk of developing small intestinal bacteria (SIBO), a risk that may decrease with thyroid hormone treatment, an annual meeting of endocrine society in San Francisco, California, according to a study on Saturday in Endo 2025.

Now we know that people with hypothyroidism, especially autoimmune thyroiditis, are more likely to develop SIBOs, but this risk is low in those taking thyroid drugs. ,

Ruchi Mathur, MD, Director of Diabetes Outstanding Treatment and Education Center and Los Angeles, Medical in Cedar-Sinai in California, medically affiliated science and diagnostic operations of technology.

Mathur said that his research also shows that there may be a microorganological mechanism running this association, which can lead to more personal treatment.

Researchers examined the relationship between SIBO and Hypothyroidism in people over the age of 18, who first passed through the upper endoscopy without a colon and reported to live with control with hypothyroidism. The subjects were recruited through his leading remagin study.

He analyzed small bowel fluid samples from 49 people with hypothyroidism and demonstrated DNA sequencing to identify microbial species without a 323 position. The results showed that people with hypothyroidism had a significant circulation of Sibo than control (33% vs. 15%).

Mathur and colleagues further evaluated four groups: sibo positive with hypothyroidism, sibo-negative with hypothyroidism, sibo positive without thyroid disease, and sibo-negative without thyroid disease.

The analysis showed various patterns of bacteria in the intestine depending on a person’s thyroid position and co-event of SIBO.

Separately, he analyzed a massive analysis of medical records from the Trinetx database, which looked at the 10-year risks of developing SIBO in people with hypothyroidism or autoimmune thyroiditis compared to matching controls. Risks were also reduced in people taking levothyroxine.

“Results showed that the risk of developing SIBO in subjects with hypothyroidism is 2.2 times higher than the risk in a matching control cohort and with autoimmune thyroiditis compared to a matching control group, it was 2.4 times more. MDIS, MDIS said.

“These findings open the door for new screening and prevention strategies. For example, the doctor can start monitoring thyroid health more closely in patients with SIBO, and on the contrary. Said. “As the research continues, this may lead to more personal care and intervention for pre -risk individuals.”